<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">foodindustry</journal-id><journal-title-group><journal-title xml:lang="ru">Пищевая промышленность: наука и технологии</journal-title><trans-title-group xml:lang="en"><trans-title>Food Industry: Science and Technology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2073-4794</issn><publisher><publisher-name>Научно-практический центр Национальной академии наук Беларуси по продовольствию</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">foodindustry-362</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Исследование полипептидных фракций пермеата обезжиренного молока, полученного методом ультрафильтрации</article-title><trans-title-group xml:lang="en"><trans-title>Investigation of polypeptide fractions of skim milk permeate obtained by ultrafiltration</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Метель</surname><given-names>В. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Metel</surname><given-names>V. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Метель Владимир Сергеевич – инженер Центра биотехнологического инжиниринга СКФУ, Института живых систем</p><p>г. Ставрополь.</p></bio><bio xml:lang="en"><p>Metel Vladimir S. – Engineer of the Center for Biotechnological Engineering of NCFU, Institute of Living Systems</p><p>Stavropol.</p></bio><email xlink:type="simple">metel@mokostav.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Куликова</surname><given-names>И. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Kulikova</surname><given-names>I. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Куликова Ирина Кирилловна – кандидат технических наук, доцент кафедры прикладной биотехнологии Института живых систем</p><p>г. Ставрополь</p></bio><bio xml:lang="en"><p>Kulikova Irina K. – PhD (Technical Sciences), Associate Professor, Department of Applied Biotechnology, Institute of Living Systems</p><p>Stavropol</p></bio><email xlink:type="simple">kik-st@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Анисимов</surname><given-names>Г. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Anisimov</surname><given-names>G. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Анисимов Георгий Сергеевич – кандидат технических наук, директор Центра биотехнологического инжиниринга СКФУ</p><p>г. Ставрополь.</p></bio><bio xml:lang="en"><p>Anisimov Georgii S. – PhD (Technical Sciences), Director of the Center for Biotechnological Engineering at North Caucasian Federal University</p><p>Stavropol</p></bio><email xlink:type="simple">ags82@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Евдокимов</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Evdokimov</surname><given-names>I. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Евдокимов Иван Алексеевич – доктор технических наук, профессор, заведующий базовой кафедрой «Технология молока и молочных продуктов»</p><p>г. Ставрополь.</p></bio><bio xml:lang="en"><p>Evdokimov Ivan A. – PhD (Technical Sciences), Professor, Head of the Basic Department of Technology of Milk and Dairy Products, FSAEI of HE «North Caucasus Federal University» at the Stavropol Dairy Plant JSC</p><p>Stavropol.</p></bio><email xlink:type="simple">ievdokimov@ncfu.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГАОУ ВО «Северо-Кавказский федеральный университет»</institution></aff><aff xml:lang="en"><institution>North-Caucasus Federal University</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>30</day><month>03</month><year>2019</year></pub-date><volume>12</volume><issue>1</issue><fpage>80</fpage><lpage>85</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Метель В.С., Куликова И.К., Анисимов Г.С., Евдокимов И.А., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Метель В.С., Куликова И.К., Анисимов Г.С., Евдокимов И.А.</copyright-holder><copyright-holder xml:lang="en">Metel V.S., Kulikova I.K., Anisimov G.S., Evdokimov I.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://foodindustry.belal.by/jour/article/view/362">https://foodindustry.belal.by/jour/article/view/362</self-uri><abstract><p>В статье рассмотрены основные пути образования пептидов в сыром обезжиренном молоке и степень перехода пептидов в пермеат при ультрафильтрационной обработке молока, приведен метод хроматографирования белковой и пептидной фракции, представлены результаты хроматографического исследования нативных молочных пептидов, находящихся в пермеате обезжиренного молока, полученного методом ультрафильтрации.</p></abstract><trans-abstract xml:lang="en"><p>The main ways of peptide formation in raw skim milk and the extent of peptides permeation in the ultrafiltration process are considered in the article. The method of chromatography of the protein and peptide fractions is described, the results of chromatographic studies of native milk peptides present in the permeate of skim milk obtained by ultrafiltration are presented.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>молоко</kwd><kwd>пермеат</kwd><kwd>ультрафильтрация</kwd><kwd>пептиды</kwd><kwd>хроматография</kwd></kwd-group><kwd-group xml:lang="en"><kwd>milk</kwd><kwd>permeate</kwd><kwd>ultrafiltration</kwd><kwd>peptides</kwd><kwd>chromatography</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Работа выполнена при финансовой поддержке Министерства образования и науки РФ, договор МОН 03.G25.31.0241.</funding-statement><funding-statement xml:lang="en">The authors would like to acknowledge financial support of the Ministry of Education and Science of the Russian Federation, contract MON 03.G25.31.0241.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Fardet, A. In vitro and in vivo antioxidant potential of milks, yoghurts, fermented milks and cheeses: a narrative review of evidence/ A. Fardet , E. Rock // Nutrition Research Reviews. - 2017. - Т. 31. - Vol. 01. - P. 1-19.</mixed-citation><mixed-citation xml:lang="en">Fardet, A. In vitro and in vivo antioxidant potential of milks, yoghurts, fermented milks and cheeses: a narrative review of evidence/ A. Fardet , E. Rock // Nutrition Research Reviews. - 2017. - Т. 31. - Vol. 01. - P. 1-19.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Morschheuser, L. Immunological analysis of food proteins using high-performance thin-layer chromatography-immunostaining / L. Morschheuser, K. Mink, R. Horst, C. Kallinich// J. Chromatogr. A. - 2017. - Т. 1526. - P. 157-166.</mixed-citation><mixed-citation xml:lang="en">Morschheuser, L. Immunological analysis of food proteins using high-performance thin-layer chromatography-immunostaining / L. Morschheuser, K. Mink, R. Horst, C. Kallinich// J. Chromatogr. A. - 2017. - Т. 1526. - P. 157-166.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Clare, D. Biodefense Properties of Milk: The Role of Antimicrobial Proteins and Peptides / D. Clare, G. Catignani, H. Swaisgood // Curr. Pharm. Des. - 2003. - Т. 9. - № 16. P. 1239-1255.</mixed-citation><mixed-citation xml:lang="en">Clare, D. Biodefense Properties of Milk: The Role of Antimicrobial Proteins and Peptides / D. Clare, G. Catignani, H. Swaisgood // Curr. Pharm. Des. - 2003. - Т. 9. - № 16. P. 1239-1255.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Li G.H. Angiotensin I-converting enzyme inhibitory peptides derived from food proteins and their physiological and pharmacological effects / G.H. Li, G.W. Le, Y.H. Shi, S. Shrestha // Nutr. Res. - 2004. - Т. 24. - № 7. - P. 469-486.</mixed-citation><mixed-citation xml:lang="en">Li G.H. Angiotensin I-converting enzyme inhibitory peptides derived from food proteins and their physiological and pharmacological effects / G.H. Li, G.W. Le, Y.H. Shi, S. Shrestha // Nutr. Res., 2004. - Т. 24. - № 7. - P. 469-486.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Korhonen, H. Bioactive Peptides from Food Proteins / H. Korhonen, A. Pihlanto // Handbook of Food Products Manufacturing. Hoboken, NJ, USA: JohnWiley&amp;Sons, Inc. - 2004 - P. 1-37.</mixed-citation><mixed-citation xml:lang="en">Korhonen, H. Bioactive Peptides from Food Proteins / H. Korhonen, A. Pihlanto // Handbook of Food Products Manufacturing. Hoboken, NJ, USA: JohnWiley&amp;Sons, Inc., 2004 - P. 1-37.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Гунькова, П.И. Влияние плазмина на свойства молока / П.И. Гунькова, К.К. Горбатова // Молочная промышленность. - 2009. - № 8. - С. 52-53.</mixed-citation><mixed-citation xml:lang="en">Gunkova, P.I., GorbatovaK.K. Vliyanie plazmina na svojstva moloka [Influence of plasmin on milk properties]. Molochnaya promyshlennost' [The dairy industry], 2009, no. 8, pp. 52-53.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Topel, A. Chemie und Physik der Milch / A. Topel // Naturstoff - Rohstoff - Lebensmittel. - Behr, 2004. - P. 362-364.</mixed-citation><mixed-citation xml:lang="en">Topel, A. Chemie und Physik der Milch / A. Topel // Naturstoff - Rohstoff - Lebensmittel. - Behr, 2004. - P. 362-364.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Цыганков, В.Г. Изучение пептидного состава ферментативного гидролизата концентрата сывороточных белков коровьего молока с целью разработки пищевых продуктов для туристическо-оздоровительной деятельности / В.Г. Цыганков, Т.Н. Головач, В.П. Курченко, А.М. Бондарук // Труды БГТУ. Минск : БГТУ, 2015. - Т. 174. - № 1. - С. 272-275.</mixed-citation><mixed-citation xml:lang="en">Tsygankov, V.G., Kurchenko V.P., Bondaruk A.M. Izuchenie peptidnogo sostava fermentativnogo gidrolizata koncentrata syvorotochnyh belkov korov'ego moloka s cel'yu razrabotki pishchevyh produktov dlya turistichesko-ozdorovitel'noj deyatel'nosti [The study of the peptide composition of the enzymatic hydrolyzate of whey protein concentrate of cow's milk with the aim of developing food products for tourist and recreational activities]. Trudy BGTU [Works BSTU]. Minsk: BSTU, 2015, T. 174. no. 1, pp. 272-275.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Brans, G. Membrane fractionation of milk: State of the art and challenges / G. Brans, C. Schroën, R. Van Der Sman, R. M. Boom // Journal of Membrane Science. - 2004. - Т. 243. - № 1-2. - P. 263-272.</mixed-citation><mixed-citation xml:lang="en">Brans, G. Membrane fractionation of milk: State of the art and challenges / G. Brans, C. Schroën, R. Van Der Sman, R. M. Boom, // Journal of Membrane Science. - 2004. - Т. 243. - № 1-2. - P. 263-272.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Pouliot, Y. Fractionation of casein hydrolysates using polysulfone ultrafiltration hollow fiber membranes / Y. Pouliot, S.F. Gauthier, C. Bard // J. Memb. Sci. - 1993. - Т. 80. - № 1. - P. 257-264.</mixed-citation><mixed-citation xml:lang="en">Pouliot, Y. Fractionation of casein hydrolysates using polysulfone ultrafiltration hollow fiber membranes / Y. Pouliot, S.F. Gauthier, C. Bard // J. Memb. Sci. - 1993. - Т. 80. - № 1. - P. 257-264.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Gourley, L. Separation of casein hydrolysates using polysulfone ultrafiltration membranes with pH and EDTA treatments applied / L. Gourley, S.F. Gauthier, Y. Pouliot // Lait. EDP Sciences - 1995. - Т. 75. - № 3. - P. 259-269.</mixed-citation><mixed-citation xml:lang="en">Gourley, L. Separation of casein hydrolysates using polysulfone ultrafiltration membranes with pH and EDTA treatments applied / L. Gourley, S.F. Gauthier, Y. Pouliot // Lait. EDP Sciences. - 1995. - Т. 75. - № 3. - P. 259-269.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Vijayalakshmi, M.A. High Performance Size Exclusion Liquid Chromatography of Small Molecular Weight Peptides from Protein Hydrolysates Using Methanol as a Mobile Phase Additive / M.A. Vijayalakshmi, L. Lemieux, J. Amiot // J. Liq. Chromatogr. Taylor&amp;FrancisGroup - 1986. - Т. 9. - № 16. - P. 3559-3576.</mixed-citation><mixed-citation xml:lang="en">Vijayalakshmi, M.A. High Performance Size Exclusion Liquid Chromatography of Small Molecular Weight Peptides from Protein Hydrolysates Using Methanol as a Mobile Phase Additive / M.A. Vijayalakshmi, L. Lemieux, J. Amiot // J. Liq. Chromatogr. Taylor&amp;FrancisGroup. - 1986. - Т. 9. - № 16. - P. 3559-3576.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Фёрстер, Э. Методы корреляционного и регрессионного анализа / Э. Фёрстер, Б. Рёнц // М.: Финансы и статистика, 1983. - 304 с.</mixed-citation><mixed-citation xml:lang="en">Forster, E., Ryants B. Metody korrelyacionnogo i regressionnogo analiza [Methods of the correlation and regression analysis]. Moscow, Finance and Statistics, 1983. - 304 p.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Nielsen, S.D. Milk bioactive peptide database: A comprehensive database of milk protein-derived bioactive peptides and novel visualization / S.D. Nielsen, R.L. Beverly, Y. Qu, D.C.Dallas // Food Chem. Elsevier. - 2017. - Т. 232. - Р. 673-682.</mixed-citation><mixed-citation xml:lang="en">Nielsen, S.D. Milk bioactive peptide database: A comprehensive database of milk protein-derived bioactive peptides and novel visualization / S.D. Nielsen, R.L. Beverly, Y. Qu, D.C.Dallas // Food Chem. Elsevier. - 2017. - Т. 232. - Р. 673-682.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
